Selected studies performed during last three years are described below:

• Černý I., Pouzar V., Hill M., Havlíková H., Hampl R.: Syntheses of 19-[O-(carboxymethyl)oxime] haptens of epipregnanolone and pregnanolone. Steroids 2006, 71(2), 120-128.
• Horák M., Vlček K., Chodounská H., Vyklický L., Jr: Subtype-dependence of N-methyl-D-aspartate receptor modulation by pregnenolone sulfate. Neuroscience 2006, 137(1), 93-102.
• Petrovič M., Sedláček M., Horák M., Chodounská H., Vyklický L., Jr. 20-oxo-5b-pregnan-3a-yl sulfate is a use-dependent NMDA receptor inhibitor. J. Neurosci. 2005, 25(37), 8439-8450.
• Kasal A., Matyáš L, Buděšínský M.: Neurosteroid analogues: synthesis of 6-aza-allopregnanolone. Tetrahedron 2005, 61(9), 2269-2278.
• Pouzar V., Černý I., Hill M., Bičíková M., Hampl R.: Derivatives of 16a-hydroxy-dehydroepiandrosterone with an additional 7-oxo or 7-hydroxy substituent: synthesis and gas chromatography/mass spectrometry analysis. Steroids 2005, 70(11), 739-749.
• Hill M., Popov P., Havlíková H., Kancheva L., Vrbíková J., Kancheva R., Pouzar V., Černý I., Stárka L.: Altered profiles of serum neuroactive steroids in premenopausal women treated for alcohol addiction. Steroids 2005, 70(8), 515-524.
• Buděšínský M., Fajkoš J., Günter J., Kasal A.: Synthesis, Reactions, Conformation Analysis, and NMR Spectra of 5,10-Epoxy-5x,10x-Estrane-3,17-Diones. Collect. Czech. Chem. Commun. 2005, 70(4), 507-518.
• Lim J. C., Park J. H., Buděšínský M., Kasal A., Han Y. H. , Koo B. S. , Lee S. I., Lee D. U. Antimutagenic constituents from the thorns of Gleditsia sinensis. Chem. Pharm. Bull. 2005, 53(5), 561-564.
• Hill M., Popov P., Havlíková H., Kancheva L., Vrbíková J., Meloun M., Kancheva R., Cibula D., Pouzar V., Černý I., Stárka L.: Reinstatement of serum pregnenolone isomers and progesterone during alcohol detoxification therapy in premenopausal women. Alcoholism 2005, 29(6), 1010-1017.
• Hill M., Havlíková H., Vrbíková J., Kancheva R., Kancheva L., Pouzar V., Černý I., Stárka L.: The identification and simultaneous quantification of 7-hydroxylated metabolites of pregnenolone, dehydroepiandrosterone, 3b,17b-androstenediol, and testosterone in human serum using gas chromatography-mass spectrometry. J. Steroid. Biochem. Mol. Biol. 2005, 96(2), 187-200.
• Pařízek A., Hill M., Kancheva R., Havlíková H., Kancheva L., Cindr J., Pašková A., Pouzar V., Černý I., Drbohlav P., Hájek Z., Stárka L.: Neuroactive pregnanolone isomers during pregnancy. J. Clin. Endocrinol. Metab. 2005, 90(1), 395-403.
• Chodounská H., Pouzar V., Buděšínský M., Slavíková B., Kohout L.: Synthesis of 3-methyl-3-hydroxy-6-oxo-androstane derivatives. Steroids 2004, 69(10), 605.
• Černý I., Havliková H., Hill M., Hampl R., Pouzar V.: Synthetic Approach to 5a-Pregnanolone 19-[O-(Carboxymethyl)oxime] Derivatives. Collect. Czech. Chem. Commun. 2004, 69(9), 1805-1817.
• Matyáš L., Kasal A., Riera Z.B., Sunol C. E.: Effects of 3a-Amino-5a-pregnan-20-one on GABA_A Receptor: Synthesis, Activity and Cytotoxicity. Collect. Czech. Chem. Commun. 2004, 69(7), 1506-1516.
• Horák M., Vlček K., Petrovič M., Chodounská H., Vyklický L., Jr.: Molecular Mechanism of Pregnenolone Sulfate Action at NR1/NR2B Receptors. J. Neurosci. 2004, 24(46), 10318-10325.
• Černý I., Pouzar V., Buděšínský M., Bičíková M., Hill M., Hampl R.: Synthesis of [19-2H3]-analogs of dehydroepiandrosterone and pregnenolone and their sulfates. Steroids 2004, 69(3), 161-171.
• Pouzar V., Černý I., Lapčík O., Hill M., Hampl R.: Synthesis of Two New Haptens of 16a-Hydroxydehydroepiandrosterone (3b,16a-Dihydroxyandrost-5-en-17-one). Steroids 2003, 68(3), 149-158.
• Klak J., Hill M., Pařízek A., Havlíková H., Bičíková M., Hampl R., Fait T., Šulcová J., Pouzar V., Kancheva R., Stárka L.: Pregnanolone isomers, pregnenolone and their polar conjugates around partituration. Physiol. Res. 2003, 52(2), 211-221.

• Šíša M., Hniličková J., Swaczynová J., Kohout L.: Syntheses of new androstane brassinosteroids with 17b-ester groups - butyrates, heptafluorobutyrates and laurates. Steroids 2005, 70(11), 755-762.
• Zullo M. A. T., Kohout L., de Azevedo M. B. M.: Semisystematic Nomenclature of brassinosteroids, Plant Growth Regulation 2004, 42(1), 15-28.
• Strnad M., Kohout L.: Simple brassinolide analogue 2a,3a-dihydroxy-17b(3-methyl-butyryloxy)-7-oxa-B-homo-5a-androstan-6-one inducing the second bean internode splitting. Plant Growth Regulation 2003, 40(1), 39-47.
• Franěk F., Eckschlager T., Kohout L.: 24-Epibrassinolide at subnanomolar concentrations modulates growth and production characteristics of a mouse hybridoma. Collect. Czech. Chem. Commun. 2003, 68(11), 2190-2200.
• Šíša M., Buděšínský M., Kohout L.: Synthesis of 7a-homo- and 7a,7b-bishomo-5a-cholestane analogues of brassinolide. Collect. Czech. Chem. Commun. 2003, 68(11), 2171-2189.

• Drašar P., Buděšínský M., Reschel M., Pouzar V., Černý I.: Etienic etienate as synthon for the synthesis of steroid oligoester gelators. Steroids 2005, 70(9), 615-625.
• Zelenka K., Trnka T., Tišlerová I., Král V., Dukh M., Drašar P.: Synthesis of porphyrin receptors modified by glycosylated steroids. Collect. Czech. Chem. Commun. 2004, 69(5), 1149-1160.
• Dukh M., Šaman D., Lang K., Pouzar V., Černý I., Drašar P., Král V.: Steroid porphyrin conjugate for saccharide sensing in protic media. Org. Biomol. Chem. 2003, 1(19), 3458-3463.
• Dukh M., Šaman D., Kroulík J., Černý I., Pouzar V., Král V., Drašar P.: Metal Coordination as a Tool for Controlling the Self-Assembling and Gelation Properties of Novel Type Cholic Amide-Phenanthroline Gelating Agent. Tetrahedron 2003, 59(23), 4069-4076.

• Gehrig-Burge K., Kohout L., Gimp G.: A novel cholesterol-based detergent, FEBS Journal 2005, 272(3), 800-812.
• Bryan M. B., Scott A. P., Černý I., Young B. A., Li W.: 15a-Hydroxyprogesterone in male sea lampreys, Petromyzon marinus L.. Steroids 2004, 69(7), 473-481.
• Bryan M. B., Scott A. P., Černý I., Yun S. S., Li W.: 15a-Hydroxytestosterone produced in vitro and in vivo in the sea lamprey, Petromyzon marinus. Gen. Comp. Endocrinol. 2003, 132(3), 349-500.