irena g. stará irena g. stará
Senior Scientist, Project Leader

Chemistry of Functional Molecules
Institute of Organic Chemistry and Biochemistry ASCR
Flemingovo nám. 2, CZ-166 10 Prague 6, Czech Republic

Phone: (+420) 220 183 315
Fax: (+420) 220 183 560
E-mail: stara@uochb.cas.cz
http://www.uochb.cas.cz/~organic

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Irena G. Stará - Background

Personal data

Born in Prague, Czech Republic
Married

Professional preparation

1993 Ph.D. (CSc.) in organic chemistry, Academy of Sciences of the Czech Republic, under Dr. J. Závada at the Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague
1988 M.Sc. (RNDr.) in bioorganic chemistry, Charles University, Prague, under Prof. P. Kočovský

Experience

2000/2001 Research assistant with Prof. P. Kočovský, University of Glasgow, United Kingdom
1993/1994 Postdoctoral fellow with Prof. W. Oppolzer, Université de Genève, Switzerland

Appointments

Currently Senior Scientist and a Project Leader in the Group of Organic Synthesis, Department of Organic Chemistry, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague
Since 1993 She has joined the Department of Organic Chemistry, Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, Prague

Research interest

Organic synthesis, asymmetric catalysis, organometallic chemistry, and, more recently, molecular devices.

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Irena G. Stará - Selected Papers

Starý, I.; Stará, I. G.; Alexandrová, Z.; Sehnal, P.; Teplý, F.; Šaman, D.; Rulíšek, L.
Pure Appl. Chem. 2006, 78, 495-499.
Helicity Control in the Synthesis of Helicenes and Related Compounds.

Hrdina, R.; Stará, I. G.; Dufková, L.; Mitchel, S.; Císařová, I.; Kotora, M.
Tetrahedron 2006, 62, 968-976.
Synthesis of Atropoisomeric Pyridines via Cobalt-Catalyzed Cocyclomerization of Diynes with Benzonitrile.

Stará, I. G.; Alexandrová, Z.; Teplý, F.; Sehnal, P.; Starý, I.; Šaman, D.; Buděšínský, M.; Cvačka J.
Org. Letters 2005, 7, 2547-2550.
Asymmetric Synthesis of [7]Helicene-Like Molecules.

Teplý, F.; Stará, I. G.; Starý, I.; Kollárovič, A.; Šaman, D.; Fiedler, P.; Vyskočil, Š.
J. Org. Chem. 2003, 68, 5193-5197.
Synthesis of 3-Hexahelicenol and Its Transformation to 3-Hexahelicenyl Amines, Diphenylphosphine, Methyl Carboxylate, and Dimethylthiocarbamate.

Teplý, F.; Stará, I. G.; Starý, I.; Kollárovič, A.; Šaman, D.; Fiedler, P.
Tetrahedron 2002, 58, 9007-9018.
Transition Metal Control in the Reaction of Alkyne-Substituted Phenyl Iodides with Terminal Alkynes: Sonogashira Coupling vs. Cyclic Carbopalladation.

Teplý, F.; Stará, I. G.; Starý, I.; Kollárovič, A.; Šaman, D.; Rulíšek, L.; Fiedler, P.
J. Am. Chem. Soc. 2002, 124, 9175-9180.
Synthesis of [5]-, [6]-, and [7]Helicene via Ni(0)- or Co(I)-Catalyzed Isomerization of Aromatic cis,cis-Dienetriynes.

Malkov, A. V.; Bella, M.; Stará, I. G.; Kočovský, P.
Tetrahedron Lett. 2001, 42, 3045-3048.
Modular Pyridine-Type P,N-Ligands Derived from Monoterpenes: Application in Asymmetric Heck Addition.

Hocek, M.; Stará, I. G.; Starý, I.; Dvořáková, H.
Tetrahedron Lett. 2001, 42, 519-521.
Cyclotrimerization of 6-Ethynyl Purines. Synthesis of 1,2,4- and 1,3,5-Tris(purin-6-yl)benzenes as Novel Hoogsteen-Triplet Analogues.

Stará, I. G.; Kollárovič, A.; Teplý, F.; Starý, I.; Šaman, D.; Fiedler, P.
Collect. Czech. Chem. Commun. 2000, 65, 577-609.
Synthesis of Aromatic Triynes as Precursors to Helicene Derivatives.

Stará, I. G.; Starý, I.; Kollárovič, A.; Teplý, F.; Vyskočil, Š.; Šaman, D.
Tetrahedron Lett. 1999, 40, 1993-1996.
Transition Metal Catalysed Synthesis of Tetrahydro Derivatives of [5]-, [6]- and [7]Helicene.

Abbott, A. P.; Cheung, C. S. M.; Lonergan, G. R.; Stará, I. G.; Starý, I.; Kočovský, P.
J. Chem. Soc., Chem. Commun. 1999, 641-642.
Electrochemistry of Quaternary Ammonium Binaphthyl Salts.

Stará, I. G.; Starý, I.; Kollárovič, A.; Teplý, F.; Šaman, D.; Tichý, M.
J. Org. Chem. 1998, 63, 4046-4050.
A Novel Strategy for the Synthesis of Molecules with Helical Chirality. Intramolecular [2+2+2] Cycloisomerization of Triynes under Cobalt Catalysis.

Stará, I. G.; Starý, I.; Tichý, M.; Závada, J.; Hanuš, V.
J. Am. Chem. Soc. 1994, 116, 5084-5088.
Stereochemical Dichotomy in the Stevens Rearrangement of Axially Twisted Dihydroazepinium and Dihydrothiepinium Salts.
A Novel Enantioselective Synthesis of Pentahelicene.

Stará, I. G.; Starý, I.; Tichý, M.; Závada, J.; Fiedler, P.
J. Org. Chem. 1994, 59, 1326-1332.
Nucleophilic Attack on 4,5-Dihydro-4-alkyl-3H-binaphth[2,1-c:1',2'-e]thiepinium Salts. A Convenient Approach
to New 2,2'-Bidentate 1,1'-Binaphthalene Ligands with Sulfur Donor Atoms.

Starý, I.; Stará, I. G.; Kočovský, P.
Tetrahedron Lett. 1993, 34, 179-182.
Allylic Alcohols as Substrates for the Palladium(0)-Catalyzed Allylic Substitution.

Stará, I. G.; Starý, I.; Závada, J.
J. Org. Chem. 1992, 57, 6966-6969.
Nucleophilic Cleavage of 4,5-Dihydro-3H-dinaphth[2,1-c:1',2'-e]azepinium Quaternary Salts. A Convenient Approach to New Axially Dissymmetric and Axially Asymmetric Ligands.

Kočovský, P.; Stieborová, I.
Tetrahedron Lett. 1989, 30, 4295-4298.
Synthesis of Strophanthidin.

Kočovský, P.; Stieborová, I.
J. Chem. Soc. Perkin Trans. 1 1987, 1969-1974.
Participation of Ambident Neighbouring Groups in Hypobromous Acid Addition to some Steroidal Olefins. Competition of Electronic and Stereoelectronic Effects.

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Irena G. Stará - Invited Lectures & Conference Talks
[abroad or international meetings]


2006

Graduate School of Engineering, Kyoto University, Kyoto, Japan, November 22, 2006
Chemistry of Helicenes and Their Congeners

Graduate School of Engineering, Hiroshima University, Higashi-Hiroshima, Japan, November 21, 2006
Chemistry of Helicenes and Their Congeners

Okayama University, Okayama, Japan, November 20, 2006
Chemistry of Helicenes and Their Congeners

Graduate School of Engineering Science, Osaka University, Osaka, Japan, October 13, 2006
Helicenes: What Man Can and Nature Cannot

1st European Chemistry Congress, Budapest, Hungary, August 27 - 31, 2006
A Straightforward Access to Racemic and Optically Pure Azahelicenes.

University of Bourgogne, Dijon, France, January 6, 2006
Helical Aromatics: Promising Materials for Chemistry and Nanoscience.



2005

University of Montpellier, France, December 14, 2005
Helically Chiral Aromatics: Their Synthesis and Properties.

CEMES-CNRS, Toulouse, France, November 2, 2005.
Helical Aromatics: Promising Materials for Molectronics.

Congres SFC-EuroChem, Nancy-2005, Univresité H. Poincaré, Vandoeuvre-les-Nancy, France, August 28 - September 1, 2005.
Innovated Synthesis of Helicenes Based on Triyne [2+2+1] Cycloisomerization.

One-day Organic Chemistry Symposium, University of Fribourg, Switzerland, July 22, 2005.
Helically Chiral Aromatics: Their Synthesis and Properties.



2004

14th International Symposium on Homogeneous Catalysis, Munich, Germany, July 5-9, 2004.
A Novel Organometallic Approach to Nonracemic Helicenes.

Chemiedozententagung, University of Dortmund, Germany, March 8-10, 2004.
An Organometallic Approach to Nonracemic Helicenes and Their Derivatives.



2003

University of Ljubljana, Slovenia, June 19, 2003.
Stereoselective Syntheses of Helicenes.



2002

Université Paul Sabatier, Toulouse, France, April 30, 2002.
Helicenes: Artificial Molecules with Helical Chirality.



2001

Cz-Pl-D-Younger Chemist Meeting 2001, Regensburg, Germany, March 16-17, 2001.
The Novel Route to Helically Chiral Molecules via [2+2+2] Cycloisomerization of Triynes.



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