Name Šmídková Markéta
Position Scientist
Markéta Šmídková  

Markéta Šmídková, Ph.D.


Biochemical Pharmacology of Antimetabolites
Institute of Organic Chemistry and Biochemistry ASCR, v.v.i.
Flemingovo nám. 2, CZ-166 10 Prague 6, Czech Republic

☎: (+420) 220 183 393


2001-2009 Ph.D. in biochemistry, Charles University, Faculty of Science, Prague.
2003 RNDr. in biochemistry, Charles University, Faculty of Science, Prague.
1996-2001 M.Sc. in biochemistry, Charles University, Faculty of Science, Prague.
2004 (1 month) Short term stay in group of Dr. Martin Müller, Deutsches Krebsforschungs-Zentrum, Heidelberg, Germany.
2005 (6 months) Marie Curie Fellowship: "Testing Transgenic Plant Products for Agriculture". Centre for Plant Sciences, Leeds University, Leeds, UK, Laboratory of Dr. Andrew Cuming.
since 2011 Postdoctoral Fellow, Biochemical Pharmacology of Antimetabolites, Institute of Organic Chemistry and Biochemistry, Prague.
2001-2011 Institute of Experimental Botany, Academy of Science of Czech Republic, Prague, Laboratory of molecular farming and DNA repair.
Research interest
Biochemical evaluation of the purine inhibitors of xanthine oxidoreductase.
Crystal structure of the enzyme:inhibitor complexes.
List of publications
Šmidková M., Špundová M., Mareèek Z., Entlicher G. (2003):
Effect of drugs on cholesterol crystallization in an artificial bile model and relation of this effect to drug binding to albumin.
Fundam. Clin Pharmacol. 17: 331-9

Šmidková M., Müller M., N. Thönes N., Piuko K., Angelisová P., J. Veleminský J., Angelis K.J. (2010):
Transient expression of human papillomavirus type 16 virus-like particles in tobacco and tomato using a tobacco rattle virus expression vector.
Biol. Plant. 54: 451-460

Šmidková M., Holá M., Angelis K.J. (2010):
Efficient biolistic transformation of the moss Physcomitrella patens.
Biol. Plant. 54: 777-780

Šmídková M., Holá M., Brouzdová J., Angelis K.J. (2011):
"Plant production of vaccine against HPV, a new perspective?".
Human Papillomavirus / Book 2. ISBN 979-953-307-684-2