Iva Pichová


This laboratory focuses on functional and structural studies of key proteins from different human pathogens and their interactions with cellular proteins and machineries. Research projects involve protein engineering, protein purification, protein characterization, enzymology, NMR and X-ray protein structure solution, isolation and analysis of complexes of cellular and pathogenic proteins, various molecular biological methods, and electron microscopy analysis. Our close cooperation with organic chemists facilitates multidisciplinary research focused on identification and characterization of enzymes involved in drug metabolism and testing of potential compounds. The group is a member of the Gilead Sciences & IOCB Research Centre and NPU 1 project.