GSRC GSRC

Publications 2009

99. Beššeová, I.; Otyepka, M.; Réblova, K.; Šponer, J.: "Dependence of A-RNA simulations on the choice of the force field and salt strength" Phys. Chem. Chem. Phys. 2009, 11, 10701-10711.
98. Pytelková, J.; Hubert, J.; Lepšík, M.; Šobotník, J.; Šindelka, R.; Křížková, I.; Horn, M.; Mareš, M.: "Digestive α-amylases of the flour moth Ephestia kuehniella - adaptation to alkaline environment and plant inhibitors" FEBS J. 2009, 276, 3531-3546.
97. Sehnal, P.; Stará, I. G.; Šaman, D.; Tichý, M.; Míšek, J.; Cvačka, J.; Rulíšek, L.; Chocholoušová, J.; Vacek, J.; Goryl, G; Szymonski, M.; Císařová, I.; Starý, I.: "An Organometallic Route to Long Helicenes" Proc. Natl. Acad. Sci. U. S. A. 2009, 106, 13169 13174.
96. Shroff, R.; Rulíšek, L.; Doubský, J.; Svatoš, A.: "Acid-Base-Driven Matrix-Assisted Mass Spectrometry for Targeted Metabolomics" Proc. Natl. Acad. Sci. U. S. A. 2009, 106, 10092-10096.
95. Vancoillie, S.; Rulíšek, L.; Neese, F.; Pierloot, K.: "Theoretical Description of the Structure and Magnetic Properties of Nitroxide-Cu(II)-Nitroxide Spin Triads by Means of Multiconfigurational Ab Initio Calculations" J. Phys. Chem. A 2009, 113, 6149-6157.
94. Vaněk, V.; Buděšínský, M.; Kabeleová, P.; Šanda, M.; Kožíšek, M.; Hančlová, I.; Mládková, J.; Brynda, J.; Rosenberg, I.; Koutmos, M.; Garrow, T.A.; Jiráček, J.: "Structure-Activity Study of New Inhibitors of Human Betaine-Homocysteine S-Methyltransferase" J. Med. Chem. 2009, 52, 3652-3665.
93. Hoffman, H.E.; Jirásková, J.; Ingr, M.; Zvelebil, M.; Konvalinka. J.: "Recombinant human serine racemase: Enzymologic characterization and comparison with its mouse ortholog" Protein Expr. Purif. 2009, 63, 62-67.
92. Mlčochová, P.; Bařinka, P.; Tykvart, J.; Šácha, P.; Konvalinka. J.: "Prostate-Specific Membrane Antigen and Its Truncated Form PSM´" The Prostate 2009, 69, 471-479.
91. Konvalinka, J.; Illnerová, H.; Hobza, P.; Hořejší, V.; Holý, A.; Jungwirth, P.; Pačes, V.; Martásek, P.; Zlatuška, J.: "Czech bibliometric system fosters mediocre research" Nature 2009, 460, 1079.
90. Hlouchová, K.; Barinka, C.; Konvalinka, J,; Lubkowski, J.: "Structural insight into the evolutionary and pharmacologic homology of glutamate carboxypeptidases II and III" FEBS J. 2009, 276, 4448-4462.
89. Grantz Šašková, K.; Kožíšek, M.; Řezáčová, P.; Brynda, J.; Yashina, T.; Kagan, R.K.; Konvalinka, J.: "Molecular Characterization of Clinical Isolates of Human Immunodeficiency Virus Resistant to the Protease Inhibitor Darunavir" J. Virol. 2009, 83, 8810-8818.
88. Heyda, J.; Pokorná, J.; Vrbka, L.; Vácha, R.; Jagoda-Cwiklik, B.; Konvalinka, J.; Jungwirth, P.; Vonrášek, J.: "Ion specific effects of sodium and potassium on the catalytic activity of HIV-1 protease" Phys. Chem. Chem. Phys. 2009, 11, 7599-7604.
87. Hoffman, H.E.; Jirásková, J.; Cígler, P.; Šanda, M.; Schraml, J.; Konvalinka, J.: "Hydroxamic Acids As a Novel Family of Serine Racemase Inhibitors: Mechanistic Analysis Reveals Different Modes of Interaction with the Pyridoxal-5´-phosphate Cofactor" J. Med. Chem. 2009, 52, 6032-6041.
86. Řezáčová, P.; Pokorná, J.; Brynda, J.; Kožíšek, M.; Cígler, P.; Lepšík, M.; Fanfrlík, J.; Řezáč, J.; Grantz Šašková, K.; Sieglová, I.; Plešek, J.; Šícha, V.; Grüner, B.; Oberwinkler, H.; Sedláček, J.; Kräusslich, H.-G.; Hobza, P.; Král, V.; Kovalinka, J.: "Design of HIV Protease Inhibitors Based on Inorganic Polyhedral Metallacarboranes" J. Med. Chem. 2009, 52, 7132-7141.
85. Macíčková-Cahová, H.; Hocek, M.: "Cleavage of adenine-modified functionalized DNA by type II restriction endonucleases" Nucleic Acids Res. 2009, 37, 7612-7622.
84. Štambaský, J.; Hocek, M.; Kočovský, P.: "C-Nucleosides: Synthetic Strategies and Biological Applications" Chem. Rev. 2009, 109, 6729-6764.
83. Doláková, P.; Dračínský, M.; Masojídková, M.; Šolínová, V.; Kašička, V.; Holý, A.: "Acyclic Nucleoside Bisphosphonates: Synthesis and Properties of Chiral 2-Amino-4,6-bis[(phosphonomethoxy)alkoxy]pyrimidines" Eur. J. Med. Chem. 2009, 44, 2408-2424.
82. Doláková, P.; Dračínský, M.; Fanfrlík, J.; Holý, A.: "Synthesis of Analogues of Acyclic Nucleoside Diphosphates Containing Phosphonomethylphosphinyl Moiety and Studies of Their Phosphorylation Reaction" Eur. J. Org. Chem. 2009, 7, 1082-1092.
81. Hocková, D.; Holý, A.; Masojídková, M.; Keough, D. T.; de Jersey, J.; Guddat, L. W.: "Synthesis of branched 9-[2-(2-phosphonoethoxy)ethyl]purines as a new class of acyclic nucleoside phosphonates which inhibit /Plasmodium falciparum/ hypoxanthine-guanine-xanthine phosphoribosyltransferase" Bioorg. Med. Chem. 2009, 17, 6218-6232.
80. Keough, D. T.; Hocková, D.; Holý, A.; Naesens, L.; Skinner- Adamsm, T.; de Jersey, J.; Guddat, L. W.: "Inhibition of Hypoxanthine-Guanine Phosphoribosyltransferase by Acyclic Nucleoside Phosphonates: A New Class of Antimalarial Therapeutics" J. Med. Chem. 2009, 52, 4391-4399.
79. Urban, M.; Joubert, N.; Hocek, M.; Alexander, R. E.; Kuchta, R. D.: "Herpes Simplex Virus-1 DNA Primase: A Remarkably Inaccurate yet Selective Polymerase" Biochemistry 2009, 48, 10866-10881.
78. Pomeisl, K.; Holý, A.; Pohl, R.; Horská, K.: "Use of Pd-catalyzed Suzuki-Miyaura coupling reaction in the rapid synthesis of 5-aryl-6-(phosphonomethoxy)uracils and evaluation of their inhibitory effect towards human thymidine phosphorylase" Tetrahedron 2009, 65, 8486-8492.
77. Krečmerová, M.; Holý, A.: "Syntheses of antivirals from the family of acyclic nucleoside phosphonates and their prodrugs" PharmaChem 2009, 6-9.
76. Čerňová, M.; Pohl, R.; Hocek, M.: "Switching the Regioselectivity of Direct C-H Arylation of 1,3-Dimethyluracil" Eur. J. Org. Chem. 2009, 3698-3701.
75. Hasník, Z.; Pohl, R.; Klepetářová, B.; Hocek, M.: "Synthesis of (Purin-6-yl)acetates and Their Transformations to 6-(2-Hydroxyethyl)- and 6-(Carbamoylmethyl)purines" Collect. Czech. Chem. Commun. 2009, 74, 1035-3059.
74. Riedl, J.; Horáková, P.; Šebest, P.; Pohl, R.; Havran, L.; Fojta, M.; Hocek, M.: "Tetrathiafulvalene-Labelled Nucleosides and Nucleoside Triphosphates: Synthesis, Electrochemistry and the Scope of Their Polymerase Incorporation into DNA" Eur. J. Org. Chem. 2009, 3519-3525.
73. Štefko, M.; Pohl, R.; Hocek, M.: "Synthesis of benzamide-C-ribonucleosides by Pd-catalyzed aminocarbonylations" Tetrahedron 2009, 65, 4471-4483.
72. Klusák, V.; Bařinka, C.; Plechanovová, A.; Mlčochová, P.; Konvalinka, J.; Rulíšek, L.; Lubkowski, J.: "Reaction Mechanism of Glutamate Carboxypeptidase II Revealed by Mutagenesis, X-ray Crystallography, and Computational Methods" Biochemistry 2009, 48, 4126-4138.
71. Hřebabecký, H.; Dračínský, M.; De Palma, A. M.; Neyts, J.; Holý, A.: "Synthesis of novel carbocyclic nucleoside analogues derived from 7-oxabicyclo[2.2.1]heptane-2-methanol" Collect. Czech. Chem. Commun. 2009, 74, 487-502.
70. Hřebabecký, H.; Dračínský, M.; De Palma, A. M.; Neyts, J.; Holý, A.: "Synthesis of novel Racemic carbocyclic nucleoside analogues derived from 4,8-dioxatricyclo[4.2.1.03,7]nonane-9-methanol and 4-oxatricyclo[4.3.1.03,7]decane-10-methanol, compounds with activity against Coxsackie viruses" Collect. Czech. Chem. Commun. 2009, 74, 469-485.
69. Mlčochová, P.; Bařinka, C.; Tykvart, J.; Šácha, P.; Konvalinka, J.: "Prostate-Specific Membrane Antigen and Its Truncated Form PSM'" Prostate 2009, 69, 471-479.
68. Hasník, Z.; Pohl, R.; Klepetářová, B.; Hocek, M.: "Cross-Coupling Reactions of Halopurines with Aryl- and Alkyltrifluoro­borates; The Scope and Limitations in the Synthesis of Modified Purines" Synthesis 2009, 1309-1317.
67. Klečka, M.; Pohl, R.; Klepetářová, B.; Hocek, M.: "Direct C-H borylation and C-H arylation of pyrrolo[2,3-d]pyrimidines: synthesis of 6,8-disubstituted 7-deazapurines" Org. Biomol. Chem. 2009, 7, 866-868.
66. Vrábel, M.; Horáková, P.; Pivoňková, H.; Kalachova, L.; Černocká, H.; Cahová, H.; Pohl, R.; Šebest, P.; Havran, L.; Hocek, M.; Fojta, M.: "Base-Modified DNA Labeled by [Ru(bpy)3]2+ and [Os(bpy)3]2+ Complexes: Construction by Polymerase Incorporation of Modified Nucleoside Triphosphates, Electrochemical and Luminescent Properties, and Applications" Chem. Eur. J. 2009, 15, 1144-1154.
65. Kalachova, L.; Pohl, R.; Hocek, M.: "Synthesis of 2'-Deoxyuridine and 2'-Deoxycytidine Nucleosides Bearing Bipyridine and Terpyridine Ligands at Position 5" Synthesis 2009, 105-112.
64. Hoffman, H. E.; Jirásková, J.; Ingr, M.; Zvelebil, M.; Konvalinka, J.: "Recombinant human serine racemase: Enzymologic characterization and comparison with its mouse ortholog" Protein Expr Purif. 2009, 63, 62-67.
.: Home | Contact | IOCB | Gilead :.