| 27. |
Pomeisl, K.; Votruba, I.; Holý, A.; Pohl, R.: "Syntheses of Pyrimidine Acyclic Nucleoside Phosphonates as Potent Inhibitors of Thymidine Phosphorylase (PD-ECGF) from SD-lymphoma" Nucleosides, Nucleotides Nucleic Acids 2007, 26, 1025-1028. |
| 26. |
Nencka, R.; Votruba, I.; Hřebabecký, H.; Jansa, P.; Tloušťová, E.; Horská, K.; Masojídková, H.; Holý, A.: "Discovery of 5-Substituted-6-chlorouracils as Efficient Inhibitors of Human Thymidine Phosphorylase" J. Med. Chem. 2007, 50, 6016-6023. |
| 25. |
Vrbková, S.; Dračínský, M.; Holý, A.: "Bifunctional acyclic nucleoside phosphonates: 2. Symmetrical 2-{[bis(phosphono)methoxy]methyl}ethyl derivatives of purines and pyrimidines" Collect. Czech. Chem. Commun. 2007, 72, 965-983. |
| 24. |
Duraffour, S.; Snoeck, R.; Krečmerová, M.; van Den Oord, K.; De Vos, R.; Holý, A.; Crance, J.-M.; Garin, D.; De Clercq. E.; Andrei, G.: "Activities of several classes of acyclic nucleoside phosphonates against camelpox virus replication in different cell culture models" Antimicrob. Agents Chemother. 2007, 51, 4410-4419. |
| 23. |
Krečmerová, M.; Holý, A.; Pohl, R.; Masojídková, M.; Andrei, G.; Naesens, L.; Neyts, J.; Balzarini, J.; De Clercq, E.; Snoeck, R.: "Ester prodrugs of cyclic 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]-5-azacytosine: Synthesis and antiviral activity" J. Med. Chem. 2007, 50, 5765-5772. |
| 22. |
Brázdilová, P.; Vrábel, M.; Pohl, R.; Pivoňková, H.; Havran, L.; Hocek, M.; Fojta, M.: "Ferrocenylethynyl Derivatives of Nucleoside Triphosphates: Synthesis, Incorporation, Electrochemistry and Bioanalytical Applications" Chem. Eur. J. 2007, 13, 9527-9533. |
| 21. |
Kožíšek, M.; Bray, J.; Řezáčová, P.; Šašková, K.; Brynda, J.; Pokorná, J.; Mammano, F.; Rulíšek, L.; Konvalinka, J.: "Molecular Analysis of the HIV-1 Resistance Development: Enzymatic Activities, Crystal Structures, and Thermodynamics of Nelfinavir-resistant HIV Protease Mutants" J. Mol. Biol. 2007, 374, 1005-1016. |
| 20. |
Čerňa, I.; Pohl, R.; Hocek, M.: "The first direct C-H arylation of purine nucleosides" Chem. Commun. 2007, 4729-4730. |
| 19. |
Krečmerová, M.; Holý, A.; Pískala, A.; Masojídková, M.; Andrei, G.; Naesens, L.; Neyts, J.; Balzarini, J.; De Clercq, E.; Snoeck, R.: "Antiviral activity of triazine analogues of 1-(S)-[3-hydroxy-2-(phosphonomethoxy)propyl]cytosine (cidofovir) and related compounds" J. Med. Chem. 2007, 50, 1069-1077. |
| 18. |
Renders, M.; Emmerechts, G.; Rozenski, J.; Krečmerová, M.; Holý, A.; Herdewijn, P.: "Enzymatic synthesis of phosphonomethyl oligonucleotides by therminator polymerase" Angew. Chem. Int. Ed. 2007, 46, 2501-2504. |
| 17. |
Lebeau, I.; Andrei, G.; Krečmerová, M.; De Clercq, E.; Holý, A.; Snoeck, R.: "Inhibitory activity of three classes of acyclic nucleoside phosphonates against murine polyomavirus and primate SV 40 strains" Antimicrob. Agents Chemother. 2007, 51, 2268-2273. |
| 16. |
Krečmerová, M.; Holý, A.; Masojídková, M.: "Pyrimidine Acyclic Nucleotide Analogues with Aromatic Substituents in C-5 Position" Collect. Czech. Chem. Commun. 2007, 72, 927-951. |
| 15. |
Doláková, P.; Masojídková, M.; Holý, A.: "Efficient Synthesis of Pyrimidinecarbonitriles and Their Derivatives" Heterocycles 2007, 71, 1107-1115. |
| 14. |
Vrbková, S.; Dračínský, M.; Holý, A.: "Bifunctional acyclic nucleoside phosphonates: synthesis of chiral 9-{3-hydroxy[1,4-bis(phosphonomethoxy)]butan-2-yl} derivatives of purines" Tetrahedron: Asymmetry 2007, 18, 2233-2247. |
| 13. |
Mlčochová, P.; Plechanovová, A.; Bařinka, C.; Mahadeva, D.; Saldanha, C.; Rulíšek, L.; Konvalinka, J.: "Mapping of the active site of glutamate carboxypeptidase II by site-directed mutagenesis" FEBS J 2007, 274, 4731-4741. |
| 12. |
Joubert, N.; Pohl, R.; Klepetářová, B.; Hocek, M.: "Modular and Practical Synthesis of 6-Substituted Pyridin-3-yl C-Nucleosides" J. Org. Chem. 2007, 72, 6797-6805. |
| 11. |
Vrábel, M.; Pohl, R.; Klepetářová, B.; Votruba, I.; Hocek, M.: "Synthesis of 2'-deoxyadenosine nucleosides bearing bipyridine-type ligands and their Ru-complexes in position 8 through cross-coupling reactions" Org. Biomol. Chem. 2007, 5, 2849–2857. |
| 10. |
Bařinka, C.; Rovenská, M.; Mlčochová, P.; Hlouchová, K.; Plechanovová, A.; Majer, P.; Tsukamoto, T.; Slusher, B. S.; Konvalinka, J.; Lubkowski, J.: "Structural Insight into the Pharmacophore Pocket of Human Glutamate Carboxypeptidase II" J. Med. Chem. 2007, 50, 3267-3273. |
| 9. |
Hasník, Z.; Šilhár, P.; Hocek, M.: "Synthesis of (purin-6-yl)acetates and 6-(2-hydroxyethyl)purines via cross-couplings of 6-chloropurines with the Reformatsky reagent" Tetrahedron Lett. 2007, 48, 5589-5592. |
| 8. |
Čapek, P.; Cahová, H.; Pohl, R.; Hocek, M.; Gloeckner, C.; Marx, A.: "An Efficient Method for the Construction of Functionalized DNA Bearing Amino Acid Groups through Cross-Coupling Reactions of Nucleoside Triphosphates Followed by Primer Extension or PCR" Chem. Eur. J. 2007, 13, 6196-6203. |
| 7. |
Pomeisl, K.; Holý, A.; Pohl, R.: "Pd-catalyzed Suzuki-Miyaura coupling reactions in the synthesis of 5-aryl-1-[2-(phosphonomethoxy)ethyl]uracils as potencial multisubstrate inhibitors of thymidine phosphorylase" Tetrahedron Lett. 2007, 48, 3065-3067. |
| 6. |
Hlouchová, K.; Bařinka, C.; Klusák, V.; Šácha, P.; Mlčochová, P.; Majer, P.; Rulíšek, L.; Konvalinka, J.: "Biochemical characterization of human glutamate carboxypeptidase III" J. Neurochem. 2007, 101, 682-696. |
| 5. |
Zábranská, H.; Tůma, R.; Kluh, I.; Svatoš, A.; Ruml, T.; Hrabal, R.; Pichová, I.: "The Role of the S-S Bridge in Retroviral Protease Function and Virion Maturation" J. Mol. Biol. 2007, 365, 1493-1504. |
| 4. |
Vrábel, M.; Hocek, M.; Havran, L.; Fojta, M.; Votruba, I.; Klepetářová, B.; Pohl, R.; Rulíšek, L.; Zendlová, L.; Hobza, P.; Shih, I.; Mabery, E.; Mackman, R.: "Purines Bearing Phenanthroline or Bipyridine Ligands and Their RuII Complexes in Position 8 as Model Compounds for Electrochemical DNA Labeling - Synthesis, Crystal Structure, Electrochemistry, Quantum Chemical Calculations, Cytostatic and Antiviral Activity" Eur. J. Inorg. Chem. 2007, 1752-1769. |
| 3. |
Bařinka, C.; Starková, J.; Konvalinka, J.; Lubowski, J.: "A high-resolution structure of ligand-free human glutamate carboxypeptidase II" Acta Cryst. 2007, F63, 150-153. |
